For Legal Professionals MDL-3140 Settlement Administration

Depo-Provera Lawsuit: Mass Tort Case Leads & Case Acquisition Intelligence

Lead generation strategies, legal marketing intelligence & case acquisition for mass tort law firms

Last updated: October 1, 2026 | Data sourced from JPML reports, federal court filings, and MDL Update tracking

This Depo-Provera lawsuit mass tort case leads intelligence report provides law firms with comprehensive lead generation data, case acquisition strategies, and legal marketing insights for MDL-3140. Whether you're evaluating Depo Provera mass tort case acquisition opportunities or scaling existing lead generation campaigns, this analysis covers case volume trends, plaintiff qualification criteria, and the competitive landscape for Depo-Provera lawsuit case leads.

Depo-Provera Lawsuit Case Snapshot

MDL Number MDL-3140
Full Name In Re: Depo-Provera (Depot Medroxyprogesterone Acetate) Products Liability Litigation
Presiding Judge Hon. M. Casey Rodgers, Northern District of Florida
District Court U.S. District Court, Northern District of Florida (Pensacola)
Current Case Count 6,412 pending actions (as of Oct 1, 2026)
Filing Velocity +59 cases/month (3-month avg)
Lifecycle Stage Settlement Administration
Settlement Master Settlement Agreement signed July 21, 2026; registration deadline November 30, 2026 for eligible claimants who signed with a lawyer on or before June 11, 2026 (CMO 14)
First Bellwether Trial Vacated June 15, 2026 (Toney v. Pfizer, was Dec 7, 2026) after global settlement in principle
Estimated Plaintiff Pool ~24.5% of U.S. women ages 15-49 have used Depo-Provera (CDC NSFG data)
Statute of Limitations 1-6 years (varies by state); CMO 14 requires a limitations certification from new filers diagnosed before March 27, 2024
6,412
Pending Actions
8,120%
Growth (19 mo)
Signed
Settlement (Jul 2026)
5.55x
Risk (BMJ Study)

Depo-Provera Mass Tort Litigation Overview

Core Allegations

Plaintiffs allege that Pfizer Inc. (and predecessor company Upjohn) knew or should have known about the association between depot medroxyprogesterone acetate (DMPA) and intracranial meningioma—a type of brain tumor—but failed to adequately warn patients and healthcare providers for decades. The litigation centers on failure-to-warn claims under strict products liability theory.

The scientific foundation rests on two major studies: a 2024 BMJ case-control study (n=18,061) finding a 5.55x increased odds ratio for meningioma with injectable MPA, and a 2025 JAMA Neurology study (n=10.4M) confirming 2.43x relative risk, particularly in patients with >4 years of exposure or those starting after age 31.

Key Milestones

Mar 2024
BMJ publishes French case-control study showing 5.55x risk
Feb 7, 2025
JPML creates MDL-3140, transfers to N.D. Florida
Nov 2025
JAMA Neurology publishes Cleveland Clinic study (n=10.4M)
Dec 12, 2025
FDA adds meningioma warning to prescribing information
Dec 21, 2025
Judge Rodgers orders 5 pilot cases for bellwether trials
Jun 15, 2026
Global settlement in principle reported; first bellwether trial (Toney v. Pfizer) vacated; preemption ruling postponed and Daubert hearing moved to Jul 27 (PTO 30A)
Jul 21, 2026
Master Settlement Agreement signed
Jul 27, 2026
12th case management conference (CMO 12), not a Daubert hearing; general-causation hearing set for Sept 18, 2026
Aug 10, 2026
CMO 14: registration deadline Nov 30, 2026; other MDL proceedings stayed; settlement docket limited to claimants who signed with a lawyer on or before Jun 11, 2026

Judicial Profile: Hon. M. Casey Rodgers

Judge Rodgers was appointed to the Northern District of Florida in 2003 and has served as Chief Judge. She has experience managing complex multidistrict litigation. Her case management order of December 21, 2025 established an aggressive bellwether schedule with five pilot cases—the first for December 2026 and four more for January 2027. That schedule moved the litigation quickly toward resolution: on June 15, 2026 the parties reported a global settlement in principle, and Judge Rodgers vacated the first bellwether trial and moved the general-causation hearing to July 27, 2026. The parties signed the Master Settlement Agreement on July 21, 2026, and July 27 was held as a case management conference instead.

The ruling on Pfizer's federal preemption defense was postponed on June 15, 2026 (PTO 30A), and CMO 12 set the general-causation (Rule 702) hearing on plaintiffs' experts for September 18, 2026. Under CMO 12, both rulings will apply only to ineligible plaintiffs and opt-outs.

Case Volume & Growth Trajectory for Mass Tort Case Leads

As of October 1, 2026, there are 6,412 pending actions in MDL-3140, according to the most recent JPML statistical report. This represents over 8,100% growth since the MDL was created in February 2025, making it one of the fastest-growing mass torts in the federal court system. Growth has slowed sharply since the settlement: pending cases rose by 9 in the October 2026 report, down from 109 in September.

Filing Velocity

Period Pending Net Change
Mar 2025 78 —
Apr 2025 289 +211
May 2025 236 -53
Jun 2025 348 +112
Jul 2025 435 +87
Aug 2025 550 +115
Sep 2025 806 +256
Oct 2025 1,222 +416
Nov 2025 1,225 +3
Dec 2025 1,470 +245
Jan 2026 1,752 +282
Feb 2026 2,098 +346
Mar 2026 3,099 +1,001
Apr 2026 3,490 +391
May 2026 3,769 +279
Jun 2026 5,508 +1,739
Jul 2026 5,830 +322
Aug 2026 6,294 +464
Sep 2026 6,403 +109
Oct 2026 6,412 +9

Source: JPML MDL Statistics Reports, March 2025 – October 2026

Estimated Total Addressable Plaintiff Pool

According to CDC National Survey of Family Growth data (2015-2019), approximately 24.5% of sexually experienced women ages 15-49 have ever used Depo-Provera in the United States. The Department of Health and Human Services reports approximately 302,000 women relied on Depo-Provera as their primary contraceptive in 2022 alone.

Given the incidence rate of meningioma in the general population and the elevated risk demonstrated in published studies, the potential Depo Provera lawsuit plaintiff pool extends into the tens of thousands. The October 1, 2026 JPML report shows 6,412 federal cases pending. Under CMO 14, the settlement's administrative docket is limited to eligible claimants who signed with a lawyer on or before June 11, 2026, so clients signed after that date proceed as litigating plaintiffs, not settlement participants.

Market Context: For comparison, similar pharmaceutical MDLs like Zantac (MDL-2924) reached 70,000+ cases before settlement, and Talcum Powder (MDL-2738) currently has 69,000+ pending. Depo-Provera filings have slowed sharply since the settlement: pending cases rose by 9 in the October 2026 report, down from 109 in September.

Comparison to Similar MDLs

MDL Current Count Age Stage
Depo-Provera (3140) 6,412 20 mo Settlement Administration
Hair Relaxer (3060) 12,381 30 mo Bellwether Selection
NEC Baby Formula (3026) 844 40 mo Active Trials
Paraquat (3004) 6,602 50 mo Active Trials

Plaintiff Qualification Criteria for Depo-Provera Case Acquisition

Primary Eligibility Requirements

Product Exposure

  • Depo-Provera CI (150mg intramuscular injection)
  • Received at least 2 injections (minimum 6 months of use)
  • Higher-value cases typically involve >4 years of exposure
  • Use within relevant timeframe (typically within last 15-20 years)

Diagnosed Condition

  • Primary: Intracranial meningioma (Grade 1, 2, or 3)
  • Diagnosis confirmed via MRI, CT scan, or pathology report
  • Surgical intervention (craniotomy) significantly increases case value
  • Recurrent meningiomas or multiple tumors may qualify

Documentation Required

  • Medical records confirming Depo-Provera administration
  • Pharmacy records showing injection history
  • Diagnostic imaging (MRI/CT) confirming meningioma
  • Surgical/pathology reports if applicable
  • Records sufficient to complete Plaintiff Fact Sheet

Settlement Program (CMO 14)

  • The agreement is confidential, so its full eligibility criteria are not public; the parties estimate about 80% of MDL plaintiffs are eligible
  • The no-fee administrative docket is open only to eligible claimants who signed with a lawyer on or before June 11, 2026
  • Eligible claimants must register by November 30, 2026
  • Plaintiffs ineligible because of filing date ("Limitations") or diagnosis timing relative to last use ("Latency") are separate groups

Common Disqualifiers

  • Prior meningioma diagnosis before Depo-Provera use
  • Neurofibromatosis type 2 or other hereditary conditions
  • History of radiation therapy to the head
  • Use of Depo-SubQ Provera 104 only (lower-dose subcutaneous version)
  • Expired statute of limitations (varies by state, 1-6 years)

Intake Screening Framework

Typical screening questions for Depo-Provera meningioma cases:

  1. Did you receive Depo-Provera (the birth control shot)?
  2. Approximately how many injections did you receive / how many years?
  3. When did you start? When did you stop?
  4. Have you been diagnosed with a brain tumor (meningioma)?
  5. When were you diagnosed?
  6. Did you have surgery to remove the tumor?
  7. Do you have medical records available?

Settlement & Case Valuation for Depo-Provera Lawsuit Leads

Settlement Signed; Terms Confidential

No bellwether trial was held in MDL-3140. The parties signed a Master Settlement Agreement on July 21, 2026, and CMO 12 describes it as private and confidential. No settlement amount or per-case value has been disclosed, and we do not publish projections.

Current Settlement Status

On June 15, 2026, Judge Rodgers entered an order confirming that Pfizer and the plaintiffs' leadership team reached a global settlement in principle, and the parties signed the Master Settlement Agreement on July 21, 2026. It covers "a majority of the claims in the MDL and New York state court," and the parties estimate that about 80% of MDL plaintiffs are eligible. The terms are confidential; Pfizer's second-quarter 10-Q calls them "not material to the Company's liquidity or financial condition" without disclosing an amount. CMO 12 created a no-fee administrative docket, and because this is not a class action there is no court fairness review.

What comes next: (1) the November 30, 2026 registration deadline for eligible claimants who signed with a lawyer on or before June 11, 2026 (CMO 14); (2) status conferences set for October 16, November 20 and December 18, 2026 (PTO 28; dates can change); (3) payments, which CMO 12 expects to begin rolling out by the first quarter of 2027; and (4) for plaintiffs outside the settlement, the preemption and causation questions. The preemption ruling was postponed on June 15, 2026 (PTO 30A), CMO 12 set the general-causation hearing for September 18, 2026, and those rulings will apply only to ineligible plaintiffs and opt-outs. CMO 14 stayed all other MDL proceedings.

Settlement Administration

Court-appointed roles and rules for the MDL-3140 settlement program:

Role Appointee or Rule Order
Settlement Administrator BrownGreer PLC (also handles medical liens under CMOs 15–17) CMO 13
Supplemental Compensation Fund Allocated by Matt Garretson CMOs 15–17
Settlement-fund administrator Randall Sansom CPA CMOs 15–17
Common benefit assessment 7%, taken only from lawyers' fees CBO 2

Source: N.D. Fla. MDL-3140 orders (CMO 13, August 5, 2026; Common Benefit Order 2, August 28, 2026; CMOs 15–17, September 4, 2026). No settlement amount or per-claim value has been disclosed.

Fee Structure Considerations

Mass tort contingency fees typically range from 33-40% of recovery. In MDL-3140, Common Benefit Order 2 (August 28, 2026) sets a 7% common benefit assessment (to compensate lead counsel for work benefiting all plaintiffs) that is taken only from lawyers' fees. Net recovery calculations should account for both fees and any litigation costs advanced by the firm.

Depo-Provera Case Leads, Lead Generation & Legal Marketing Landscape

Depo-Provera Mass Tort Case Lead Market Assessment

Emerging Growth Mature Declining

Current Assessment: Settlement Administration — The parties signed a Master Settlement Agreement on July 21, 2026, and filing has slowed sharply (pending cases rose by 9 in the October 2026 JPML report, down from 109 in September). Under CMO 14, the settlement's administrative docket is limited to eligible claimants who signed with a lawyer on or before June 11, 2026; people who sign with a lawyer after that date proceed as litigating plaintiffs, not settlement participants.

Depo-Provera Lawsuit Legal Marketing & Advertising Activity

TV/Radio
Moderate National campaigns visible, not yet at Camp Lejeune saturation levels
Digital (Search)
Growing Multiple law firm landing pages ranking; CPCs rising for high-intent terms
Social
Moderate Facebook/Instagram targeting available; plaintiff demographic aligns with platform usage
Lead Vendors
Active Multiple vendors offering Depo-Provera leads; quality varies significantly

Mass Tort Legal Marketing Channel Considerations

Plaintiff Demographics: Women ages 25-55 who used hormonal contraception. Higher usage rates among younger women, Black and Hispanic women, and lower-income populations (per CDC data). This demographic is reachable across multiple channels.

Digital Opportunity: The December 2025 FDA warning created significant search demand. Content-focused SEO strategies may offer better long-term ROI than pure paid acquisition in this category.

State-Level Focus: As of CMO 12 (July 2026), state courts had cases in Delaware (410), New York (129), California (118), Minnesota (72 cases with 6,899 plaintiffs), Connecticut (13 cases with 76 plaintiffs) and Illinois (12). The settlement covers a majority of the claims in the MDL and New York state court.

Depo-Provera Lawsuit Lead Generation Strategies for Mass Tort Case Acquisition

Law firms entering or scaling Depo-Provera lawsuit marketing have several lead generation approaches to consider:

1
Organic SEO & Content Marketing

Building authority through educational content targeting "Depo-Provera lawsuit," "Depo-Provera brain tumor," and related informational queries. Long-term asset that compounds over time with lower marginal acquisition costs.

2
Dedicated Niche Sites

Purpose-built microsites focused exclusively on Depo-Provera litigation can rank faster for specific case-related terms than adding pages to a general law firm site. Enables targeted messaging and conversion optimization.

3
Google Ads & Local Service Ads (LSAs)

Paid search captures high-intent queries immediately. LSAs provide Google-screened credibility and pay-per-lead pricing. Both require ongoing optimization but deliver measurable, scalable case volume.

4
Social Media Advertising

Facebook and Instagram enable demographic targeting aligned with the Depo-Provera user population. Effective for awareness and retargeting campaigns. Video creative explaining the lawsuit connection performs well.

Strategic Note: Firms combining organic SEO with paid acquisition for Depo Provera mass tort case leads typically achieve better unit economics than those relying solely on third-party lead vendors—while building owned media assets that retain value regardless of litigation outcome.

Critical Dates for Depo-Provera Mass Tort Case Leads

2026–2027 Schedule

Feb 20, 2026
Plaintiffs' response to Pfizer's preemption brief due
Feb 27, 2026
Pfizer's reply brief on preemption due
Jun 15, 2026
Global settlement in principle reported; first bellwether trial vacated; preemption ruling postponed and Rule 702 hearing moved from Jun 24-25 to Jul 27 (PTO 30A)
Jul 21, 2026
Master Settlement Agreement signed
Jul 27, 2026
12th case management conference (CMO 12), not a Daubert hearing; general-causation (Rule 702) hearing set for Sept 18, 2026, after that day's status conference
Aug 10, 2026
CMO 14: registration deadline set; all other MDL proceedings stayed; administrative docket limited to eligible claimants who signed with a lawyer on or before Jun 11, 2026
Oct 16, Nov 20, Dec 18
Status conferences (PTO 28; dates can change)
Nov 30, 2026
Settlement registration deadline for eligible claimants (CMO 14)
Q1 2027
Payments expected to begin rolling out (CMO 12)
Vacated
First bellwether trial (Toney v. Pfizer, was Dec 7, 2026) and four Jan 2027 pilots — deadlines vacated by the June 15 settlement

Statute of Limitations Considerations

Statute of limitations for Depo-Provera claims ranges from 1 to 6 years depending on the state.

The discovery rule varies by state: in many states the clock starts when the plaintiff knew or should have known about the connection between Depo-Provera and meningioma. Timing is contested in this MDL. CMO 14 requires new filers diagnosed before March 27, 2024 to file a statute-of-limitations certification within 30 days, plaintiffs ineligible for the settlement because of their filing date form a separate "Limitations" group, and CMO 12 placed three pilot cases (Yeager, Davis and Ponder) on a statute-of-limitations track.

Note: Statute of limitations varies by state and individual circumstances. Firms should conduct state-specific analysis for each potential plaintiff.

Depo-Provera Lawsuit Case Leads FAQ

How many Depo-Provera cases have been filed?

As of the October 1, 2026 JPML report, there are 6,412 pending actions in MDL-3140. As of CMO 12 (July 2026), state courts also had cases in Delaware (410), New York (129), California (118), Minnesota (72 cases with 6,899 plaintiffs), Connecticut (13 cases with 76 plaintiffs) and Illinois (12). Case count has grown over 8,100% since the MDL was created in February 2025.

Is Depo-Provera litigation still accepting new cases?

New cases can still be filed, but under CMO 14 (August 10, 2026) the settlement's no-fee administrative docket is open only to eligible claimants who signed with a lawyer on or before June 11, 2026, and those claimants must register by November 30, 2026. People who sign with a lawyer after June 11 proceed as litigating plaintiffs, not settlement participants. Newly filed plaintiffs must send records-preservation notices within 60 days, serve case-specific expert reports within 90 days, mediate, and attend an in-person conference in Pensacola, and new filers diagnosed before March 27, 2024 must file a statute-of-limitations certification within 30 days. Filing has slowed sharply: pending cases rose by 9 in the October 2026 JPML report, down from 109 in September.

What are estimated Depo-Provera settlement values?

No settlement values have been disclosed. The parties signed a Master Settlement Agreement on July 21, 2026, but CMO 12 describes it as private and confidential. Pfizer's second-quarter 10-Q describes the terms as not material to the company's liquidity or financial condition and does not disclose an amount. We do not publish projected per-case values.

How does Depo-Provera compare to other active mass torts?

Depo-Provera was one of the fastest-growing MDLs, rising from 78 pending cases in March 2025 to 6,412 in the October 2026 JPML report (over 8,100% growth in 19 months). It remains smaller than mature MDLs like Talcum Powder (69K cases) or AFFF (15K cases). Growth has slowed sharply since the parties signed a Master Settlement Agreement on July 21, 2026: pending cases rose by 9 in the October 2026 report, down from 109 in September.

When is the first Depo-Provera bellwether trial, and what did the June 2026 settlement change?

The first pilot trial (Toney v. Pfizer) had been set for December 7, 2026, with four more bellwethers to follow in January 2027. On June 15, 2026, after the parties reported a global settlement in principle, Judge Rodgers vacated the first bellwether trial and its pretrial deadlines, postponed the preemption ruling, and moved the general-causation (Daubert) hearing from June 24-25 to July 27, 2026. July 27 was held as the 12th case management conference instead, and CMO 12 set the general-causation hearing for September 18, 2026. CMO 12 also placed three new pilot cases (Yeager, Davis and Ponder) on a statute-of-limitations track, and CMO 14 stayed all other MDL proceedings.

How can law firms generate Depo-Provera lawsuit mass tort case leads?

Law firms can generate Depo-Provera lawsuit leads through several channels: organic SEO targeting lawsuit-related search terms, Google Ads for high-intent queries, Local Service Ads (LSAs) for Google-screened credibility, social media advertising on Facebook/Instagram targeting the plaintiff demographic, and dedicated niche websites built specifically for the Depo-Provera litigation. Firms investing in owned media assets (SEO, niche sites) often achieve better long-term unit economics than those relying solely on third-party lead sources.

Is SEO effective for Depo-Provera lawsuit lead generation and legal marketing?

The December 2025 FDA warning created significant search demand for Depo-Provera lawsuit information, and educational content can still reach people researching the litigation. But the litigation is no longer early-stage: the parties signed a Master Settlement Agreement on July 21, 2026, and pending cases rose by 9 in the October 2026 JPML report.

Should law firms build a dedicated site for Depo-Provera cases?

Dedicated niche sites for specific mass torts can outperform pages on a general law firm website. Benefits include: faster ranking for case-specific keywords, focused conversion optimization without competing firm priorities, cleaner attribution and analytics, and the ability to build topical authority quickly.

What paid advertising works for Depo-Provera mass tort case acquisition and lead generation?

Google Ads captures high-intent searches from women actively researching the lawsuit. Local Service Ads (LSAs) provide Google-verified credibility and pay-per-lead pricing. Facebook/Instagram ads enable demographic targeting aligned with Depo-Provera users (women 25-55) and support video creative explaining the meningioma connection. Most successful firms use a multi-channel approach with proper attribution tracking to optimize spend allocation across channels.

Is it too late to enter Depo-Provera litigation?

For the settlement, the cutoff has passed. Under CMO 14 (August 10, 2026), the settlement's no-fee administrative docket is open only to eligible claimants who signed with a lawyer on or before June 11, 2026, and those claimants must register by November 30, 2026. People who sign with a lawyer after June 11 proceed as litigating plaintiffs, not settlement participants. Newly filed plaintiffs must send records-preservation notices within 60 days, serve case-specific expert reports within 90 days, mediate, and attend an in-person conference in Pensacola, and new filers diagnosed before March 27, 2024 must file a statute-of-limitations certification within 30 days.

Can smaller firms participate in Depo-Provera litigation?

Yes. Smaller firms can sign cases and refer to or co-counsel with established mass tort firms handling the litigation. This allows participation without the overhead of MDL leadership. Referral fees typically range from 25-40% of the originating firm's fee. Alternatively, firms can build their own inventory and join the MDL directly. Cases signed after June 11, 2026 proceed in litigation rather than through the settlement (CMO 14). Digital marketing (SEO, targeted ads) has leveled the playing field, allowing nimble firms to compete effectively against larger competitors.

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Quick Reference

MDL Number 3140
Pending Cases 6,412
Growth Rate +59/mo
First Trial Vacated (settlement)
Stage Settlement Administration

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